Felix M. Key finished 2010 his undergrad in human biology at the University of Greifswald (Germany), with a major in immunology and microbiology. Felix earned a PhD (summa cum laude) in Population Genetics from the Max-Planck-Institute for Evolutionary Anthropology in Leipzig (Germany) in 2016, where he worked on human local adaptation using modern and ancient genomes. Funding was awarded by Max Planck Research School of Human Origins.
Following, Felix performed a two-year PostDoc at the Max-Planck-Institute for the Science of Human History in Jena (Germany), where he developed bioinformatic tools to study ancient microbes and reconstructed the genomes of major human pathogens from the Neolithic in order to understand their phylogenetic and adaptive history.
Felix joined the Lieberman lab at MIT in 2018, working on intrahost evolution of different pathogens part of the human microbiome during health and disease. Felix was awarded a two-year fellowship by the German Research Foundation.
Full list of publications on Google Scholar.
Link to CV.
Contact: fkey [at] mit.edu
- HOPS: Automated detection and authentication of pathogen DNA in archaeological remains
Ron Huebler*, Felix M. Key*, Christina Warinner, Kirsten I Bos, Johannes Krause, Alexander Herbig
- Human local adaptation of the TRPM8 cold receptor along a latitudinal cline
Felix M Key, Muslihudeen Abdul-Aziz, Roger Mundry, Benjamin M Peter, Mauro Sekar, Aarthi, D’Amato, Megan Y Dennis, Joshua M Schmidt, Aida M AndrésPLoS Genetics (2018)
- Mining metagenomic data sets for ancient DNA: recommended protocols for authentication
FM Key, C Posth, J Krause, A Herbig, KI BosTrends in Genetics (2017)
- Human adaptation and population differentiation in the light of ancient genomes
FM Key, Q Fu, F Romagné, M Lachmann, AM AndrésNature Communications (2016)
- Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)
Felix M Key, Benjamin Peter, Megan Y Dennis, Emilia Huerta-Sánchez, Wei Tang, Ludmila Prokunina-Olsson, Rasmus Nielsen, Aida M AndrésPLoS Genetics (2014)
- Advantageous diversity maintained by balancing selection in humans
FM Key, JC Teixeira, C de Filippo, AM AndrésCurrent Opinion in Genetics & Development (2014)